Translating Clinical Trial Evidence into a Payer-Relevant Value Narrative

Situation

  • Client had evidence from three trials but lacked a unified story across clinical, statistical, and payer audiences.
  • Existing trial endpoints did not directly connect to reimbursement and economic value measures.

Approach

  • Reviewed and organized data room materials across three studies.
  • Built a clinical and biostatistical narrative based on evidence strength and relevance.
  • Supported HCP engagement and evidence validation.
  • Created charts, diagrams, and modality visuals for cross-stakeholder communication.
  • Built a crosswalk from trial endpoints to EQ-5D, then to QALYs and ICER for payer relevant claims.

Outcome

  • Unified fragmented evidence into a coherent stakeholder-ready narrative.
  • Created a novel bridge from clinical outcomes to payer value measures.
  • Strengthened support for reimbursement and cost-effectiveness discussions.